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Carotenoids May Reduce Colon Cancer

Test results from 2,410 individuals with a history of colon cancer has revealed that lutein was inversely linked with colon cancer in both male and female subjects. The greatest inverse association was noted among subjects in whom colon cancer was diagnosed when they were young (34 percent) and among those with colon tumors (35 percent). The associations with other carotenoids were negligible.

Major dietary sources of lutein in subjects with colon cancer and in control subjects were spinach, broccoli, lettuce, tomatoes, oranges and orange juice, carrots, celery and greens.

According to the American Journal of Clinical Nutrition (2000, Vol 71, Iss 2, pp 575-582), the study was targeted at the association between dietary alpha-carotene, beta-carotene, lycopene, lutein, zeaxanthin and beta-cryptoxanthin and the risk of colon cancer. Except for beta-carotene, there is little known about how dietary carotenoids are related with common cancers including colon cancer. Carotenoids have many biological properties that may allow them to play a role as chemopreventive agents.

Information provided is courtesy of and compiled by the Academy of Anti-Aging Research staff, editors, and other reports.


Anti-Aging Perspective:

There are hundreds of carotenoids. We are just starting to research and study a few of the significant ones. The simple take-home lesson is to continue to eat whole fruits and vegetables for their rich source of carotenoids.
Incorporating broccoli, tomato, carrots, celery, and greens into the diet may help reduce the risk of developing colon cancer.

Leutin and Zeaxanthin, in particular, are strong antioxidants that help the retina and help prevent macular degeneration.


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Michael Lam, MD, MPH, ABAAM
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